Myectomy or Alcohol Septal Ablation

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Septal myectomy after failed septal alcohol ablation.

Despite septal myectomy remaining the gold standard septal reduction therapy for hypertrophic obstructive cardiomyopathy (HOCM), there has been a disproportionate use of alcohol septal ablation (ASA) worldwide. Absolute resolution of left ventricular outflow tract (LVOT) obstruction with ASA is not achieved in a substantial proportion of patients. The mechanisms of failure from ASA are partiall...

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Percutaneous Septal Alcohol Ablation after Surgical Myectomy

Hypertrophic obstructive cardiomyopathy (HOCM) is a primary, usually familial and genetically fi xed myocardial hypertrophy, with dynamic left ventricular outfl ow tract obstruction. An alternative to surgical myectomy in the treatment of severe, drug refractory, HOCM is percutaneous transluminal septal myocardial ablation (PTSMA). We report a case of  year old female patient who had the fi r...

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Surgical septal myectomy versus alcohol septal ablation: assessing the status of the controversy in 2014.

1617 I n hypertrophic cardiomyopathy (HCM), left ventricular (LV) outflow tract obstruction, caused by mitral valve sys-tolic anterior motion (SAM) with elevated intracavitary LV pressures, can produce disabling symptoms of heart failure and excess cardiovascular mortality. Outflow gradients are common in HCM, present in 70% of patients at rest or with physiological exercise 4 (Figure 1). Fifty...

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Revisiting arrhythmic risk after alcohol septal ablation: is the pendulum finally swinging…back to myectomy?

F or the past 10 years, a debate has raged within the international cardiovascular medicine community regarding treatment options for severely symptomatic and drug-refractory patients with obstructive hypertrophic cardiomyopathy (HCM) (1–21). Surgical myectomy has been the gold-standard treatment for this relatively small HCM subset since the early 1960s, with proven efficacy in abolishing left...

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Hypertrophic obstructive cardiomyopathy-alcohol septal ablation vs. myectomy: a meta-analysis.

AIMS Our purpose is to conduct a meta-analysis of all published studies comparing alcohol septal ablation (ASA) and myectomy (MM) for drug refractory hypertrophic obstructive cardiomyopathy (HOCM). Alcohol septal ablation is a less invasive alternative to MM for relief of symptoms in patients with drug refractory HOCM. METHODS AND RESULTS An extensive search of PubMed identified five non-rand...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2007

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2006.10.029